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Methylation of foreign DNA sequences in eukaryotic cells.

The herpesvirus thymidine kinase gene has been used to introduce foreign DNA sequences into mouse L cells by DNA-mediated gene transfer. These inserted genes were then assayed for methylation at the specific sequence C-C-G-G by using the restriction enzyme isoschizomers Hpa II and Msp I. Despite the...

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Detalles Bibliográficos
Main Authors: Pollack, Y, Stein, R, Razin, A, Cedar, H
Formato: Artigo
Idioma:Inglês
Publicado: 1980
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC350305/
https://ncbi.nlm.nih.gov/pubmed/6935661
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