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Methylation of foreign DNA sequences in eukaryotic cells.

The herpesvirus thymidine kinase gene has been used to introduce foreign DNA sequences into mouse L cells by DNA-mediated gene transfer. These inserted genes were then assayed for methylation at the specific sequence C-C-G-G by using the restriction enzyme isoschizomers Hpa II and Msp I. Despite the...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Pollack, Y, Stein, R, Razin, A, Cedar, H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1980
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC350305/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6935661/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.11.6463
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