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No CAG repeat expansion of polymerase gamma is associated with male infertility in Tamil Nadu, South India

Mitochondria contains a single deoxyribonucleic acid (DNA) polymerase, polymerase gamma (POLG) mapped to long arm of chromosome 15 (15q25), responsible for replication and repair of mitochondrial DNA. Exon 1 of the human POLG contains CAG trinucleotide repeat, which codes for polyglutamate. Ten copi...

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Autor principal: Poongothai, J.
Format: Artigo
Idioma:Inglês
Publicat: Medknow Publications & Media Pvt Ltd 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841557/
https://ncbi.nlm.nih.gov/pubmed/24339545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.120823
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