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Fragile X CGG Repeat Variation in Tamil Nadu, South India: A Comparison of Radioactive and Methylation-Specific Polymerase Chain Reaction in CGG Repeat Sizing

Fragile X syndrome is the most frequent hereditary cause of mental retardation after Down syndrome. Expansion of CGG repeats in the 5′ UTR of the fragile X mental retardation gene 1 (FMR1) causes gene inactivation in most of the cases. The FMR1 gene is classified into normal 5–44; gray zone 45–54; p...

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Detalhes bibliográficos
Main Authors: Indhumathi, Nagarathinam, Singh, Deepika, Chong, Samuel S., Thelma, B.K., Arabandi, Ramesh, Srisailpathy, C.R. Srikumari
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3277926/
https://ncbi.nlm.nih.gov/pubmed/22023245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2011.0102
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