Inter and intra ethnic variation of vitamin K epoxide reductase complex and cytochrome P450 4F2 genetic polymorphisms and their prevalence in South Indian population

BACKGROUND: Genetic variation in the vitamin K epoxide reductase complex (VKORC1) and cytochrome P450 4F2 (CYP4F2) genes were found to be strongly associated with the oral anticoagulant (OA) dose requirement. The distribution of genetic variation in these two genes was found to show large inter- and...

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Bibliographic Details
Main Authors: Kumar, Dhakchinamoorthi Krishna, Shewade, Deepak Gopal, Manjunath, Sajjanavar, Ushakiran, Prayaga, Reneega, Gangadharan, Adithan, Chandrasekaran
Format: Artigo
Language:Inglês
Published: Medknow Publications & Media Pvt Ltd 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841554/
https://ncbi.nlm.nih.gov/pubmed/24339542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-6866.120817
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