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Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.

The binding function of purified receptors can be assessed with radioligands, but the interaction of receptors with their biochemical effectors has not been amenable to direct study. Toward this end, procedures have been developed for directly demonstrating functionality of purified beta-adrenergic...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Proc Natl Acad Sci U S A
Príomhchruthaitheoirí: Cerione, R A, Strulovici, B, Benovic, J L, Strader, C D, Caron, M G, Lefkowitz, R J
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: National Academy of Sciences 1983
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.16.4899
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