Reconstitution of beta-adrenergic receptors in lipid vesicles: affinity chromatography-purified receptors confer catecholamine responsiveness on a heterologous adenylate cyclase system.

The binding function of purified receptors can be assessed with radioligands, but the interaction of receptors with their biochemical effectors has not been amenable to direct study. Toward this end, procedures have been developed for directly demonstrating functionality of purified beta-adrenergic...

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Bibliographische Detailangaben
Hauptverfasser: Cerione, R A, Strulovici, B, Benovic, J L, Strader, C D, Caron, M G, Lefkowitz, R J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC384154/
https://ncbi.nlm.nih.gov/pubmed/6308659
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