Integrin α(v)β(3)-Targeted Radiotracer (99m)Tc-3P-RGD(2) Useful for Noninvasive Monitoring of Breast Tumor Response to Antiangiogenic Linifanib Therapy but not Anti-Integrin α(v)β(3) RGD(2) Therapy

Purpose: (99m)Tc-3P-RGD(2) is a (99m)Tc-labeled dimeric cyclic RGD peptide that binds to integrin α(v)β(3) with high affinity and specificity. The purpose of this study was to demonstrate the utility of (99m)Tc-3P-RGD(2) SPECT/CT (single photon emission computed tomography/computed tomography) as a...

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Detalhes bibliográficos
Main Authors: Ji, Shundong, Zheng, Yumin, Shao, Guoqiang, Zhou, Yang, Liu, Shuang
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2013
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841333/
https://ncbi.nlm.nih.gov/pubmed/24312152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.6989
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