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Radiolabeled Cyclic RGD Peptides as Integrin α(v)β(3)-Targeted Radiotracers: Maximizing Binding Affinity via Bivalency
Integrin α(v)β(3) plays a significant role in tumor angiogenesis, and is a receptor for the extracellular matrix proteins with the exposed arginine-glycine-aspartic (RGD) tripeptide sequence. These include vitronectin, fibronectin, fibrinogen, lamin, collagen, Von Willibrand’s factor, osteoponin, an...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2795072/ https://ncbi.nlm.nih.gov/pubmed/19719118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900167c |
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