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The CCR4 Deadenylase Acts with Nanos and Pumilio in the Fine-Tuning of Mei-P26 Expression to Promote Germline Stem Cell Self-Renewal

Translational regulation plays an essential role in Drosophila ovarian germline stem cell (GSC) biology. GSC self-renewal requires two translational repressors, Nanos (Nos) and Pumilio (Pum), which repress the expression of differentiation factors in the stem cells. The molecular mechanisms underlyi...

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Detalhes bibliográficos
Main Authors: Joly, Willy, Chartier, Aymeric, Rojas-Rios, Patricia, Busseau, Isabelle, Simonelig, Martine
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841267/
https://ncbi.nlm.nih.gov/pubmed/24286029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.09.007
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