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A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1

Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset syndrome characterized by progressive degeneration of particular muscles. OPMD is caused by short GCG repeat expansions within the gene encoding the nuclear poly(A)-binding protein 1 (PABPN1) that extend an N-terminal polyalanine tract in t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chartier, Aymeric, Benoit, Béatrice, Simonelig, Martine
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1462976/
https://ncbi.nlm.nih.gov/pubmed/16642034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601117
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