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A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset syndrome characterized by progressive degeneration of particular muscles. OPMD is caused by short GCG repeat expansions within the gene encoding the nuclear poly(A)-binding protein 1 (PABPN1) that extend an N-terminal polyalanine tract in t...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1462976/ https://ncbi.nlm.nih.gov/pubmed/16642034 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601117 |
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