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Radioprotection of human lymphoid cells by exogenously supplied glutathione is mediated by gamma-glutamyl transpeptidase.

Human lymphoid cells depleted of glutathione by treatment with buthionine sulfoximine, a specific inhibitor of gamma-glutamylcysteine synthetase, may be partially repleted by adding glutathione in the medium. The mechanism of repletion involves the action of gamma-glutamyl transpeptidase on exogenou...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Jensen, G L, Meister, A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1983
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6136037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4714
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