Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice.

A threonine to isoleucine polymorphism at amino acid 164 in the fourth transmembrane spanning domain of the beta 2-adrenergic receptor (beta 2AR) is known to occur in the human population. The functional consequences of this polymorphism to catecholamine signaling in relevant cells or to end-organ r...

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Bibliographic Details
Main Authors: Turki, J, Lorenz, J N, Green, S A, Donnelly, E T, Jacinto, M, Liggett, S B
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC38411/
https://ncbi.nlm.nih.gov/pubmed/8816827
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