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Myocardial signaling defects and impaired cardiac function of a human beta 2-adrenergic receptor polymorphism expressed in transgenic mice.
A threonine to isoleucine polymorphism at amino acid 164 in the fourth transmembrane spanning domain of the beta 2-adrenergic receptor (beta 2AR) is known to occur in the human population. The functional consequences of this polymorphism to catecholamine signaling in relevant cells or to end-organ r...
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Главные авторы: | , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
1996
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC38411/ https://ncbi.nlm.nih.gov/pubmed/8816827 |
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