Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells.

Cotransformation with two plasmids, one [pSV2-IFN-gamma] encoding human immune interferon (Hu IFN-gamma) and the other [pAdD26SV(A)-3] encoding mouse dihydrofolate reductase, has been used to establish Chinese hamster ovary (CHO) cell lines that secrete high levels of Hu IFN-gamma. Hu IFN-gamma prod...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Scahill, S J, Devos, R, Van der Heyden, J, Fiers, W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384102/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308636/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4654
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