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Expression and characterization of the product of a human immune interferon cDNA gene in Chinese hamster ovary cells.

Cotransformation with two plasmids, one [pSV2-IFN-gamma] encoding human immune interferon (Hu IFN-gamma) and the other [pAdD26SV(A)-3] encoding mouse dihydrofolate reductase, has been used to establish Chinese hamster ovary (CHO) cell lines that secrete high levels of Hu IFN-gamma. Hu IFN-gamma prod...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Scahill, S J, Devos, R, Van der Heyden, J, Fiers, W
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1983
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6308636/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4654
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