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An experimental xenograft mouse model of diffuse pontine glioma designed for therapeutic testing

The prognosis for diffuse infiltrating pontine gliomas (DIPG) remains extremely poor, with the majority of patients surviving less than 2 years. Here, we have adapted standard xenograft techniques to study glioma growth in the mouse brainstem, and have utilized the mouse model for studying a relevan...

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Autors principals: Aoki, Yasuyuki, Hashizume, Rintaro, Ozawa, Tomoko, Banerjee, Anu, Prados, Michael, James, C. David, Gupta, Nalin
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841009/
https://ncbi.nlm.nih.gov/pubmed/22231932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-011-0796-x
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