Alpha-pyridine nucleotides as substrates for a plasmid-specified dihydrofolate reductase.
The alpha epimers of pyridine nucleotides are almost totally inactive as reductants in dehydrogenase reactions. In contrast, the R plasmid R67-specified dihydrofolate reductase (5,6,7,8-tetrahydrofolate: NADP+ oxidoreductase, EC 1.5.1.3) isolated from trimethoprim-resistant Escherichia coli utilized...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1983
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6410395/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.15.4619 |
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