Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking

Recent studies demonstrated that the antihypertensive drug Valsartan improved spatial and episodic memory in mouse models of Alzheimer’s Disease (AD) and human subjects with hypertension. However, the molecular mechanism by which Valsartan can regulate cognitive function is still unknown. Here, we i...

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Autori principali: Sohn, Young In, Lee, Nathanael J., Chung, Andrew, Saavedra, Juan M., Turner, R. Scott, Pak, Daniel T. S., Hoe, Hyang-Sook
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840727/
https://ncbi.nlm.nih.gov/pubmed/24012668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.08.091
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