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Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking

Recent studies demonstrated that the antihypertensive drug Valsartan improved spatial and episodic memory in mouse models of Alzheimer’s Disease (AD) and human subjects with hypertension. However, the molecular mechanism by which Valsartan can regulate cognitive function is still unknown. Here, we i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sohn, Young In, Lee, Nathanael J., Chung, Andrew, Saavedra, Juan M., Turner, R. Scott, Pak, Daniel T. S., Hoe, Hyang-Sook
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840727/
https://ncbi.nlm.nih.gov/pubmed/24012668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.08.091
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