ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo

The three human alleles of apolipoprotein E (APOE) differentially influence outcome after CNS injury and affect one's risk of developing Alzheimer's disease (AD). It remains unclear how ApoE isoforms contribute to various AD-related pathological changes (e.g., amyloid plaques and synaptic...

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Main Authors: Dumanis, Sonya B., Tesoriero, Joseph A., Babus, Lenard W., Nguyen, Madeline T., Trotter, Justin H., Ladu, Mary Jo, Weeber, Edwin J., Turner, R. Scott, Xu, Baoji, Rebeck, G. William, Hoe, Hyang-Sook
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2009
Assuntos:
Brief Communications
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2846754/
https://ncbi.nlm.nih.gov/pubmed/19955384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4026-09.2009
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