Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine

BACKGROUND: The purpose of the present study was to retrospectively evaluate whether copy number changes of the genes encoding the ribonucleotide reductase subunit M1 (RRM1) and/or subunit M2B (RRM2B) predict sensitivity to gemcitabine administered in combination with docetaxel compared to single ag...

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Autores principales: Jørgensen, Charlotte LT, Ejlertsen, Bent, Bjerre, Karsten D, Balslev, Eva, Nielsen, Dorte L, Nielsen, Kirsten V
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840598/
https://ncbi.nlm.nih.gov/pubmed/24215511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-541
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