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Gene aberrations of RRM1 and RRM2B and outcome of advanced breast cancer after treatment with docetaxel with or without gemcitabine
BACKGROUND: The purpose of the present study was to retrospectively evaluate whether copy number changes of the genes encoding the ribonucleotide reductase subunit M1 (RRM1) and/or subunit M2B (RRM2B) predict sensitivity to gemcitabine administered in combination with docetaxel compared to single ag...
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Autori principali: | , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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BioMed Central
2013
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840598/ https://ncbi.nlm.nih.gov/pubmed/24215511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-541 |
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