Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer

BACKGROUND: Resistance to platinum-based chemotherapy remains a major impediment in the treatment of serous epithelial ovarian cancer. The objective of this study was to use gene expression profiling to delineate major deregulated pathways and biomarkers associated with the development of intrinsic...

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主要な著者: Koti, Madhuri, Gooding, Robert J, Nuin, Paulo, Haslehurst, Alexandria, Crane, Colleen, Weberpals, Johanne, Childs, Timothy, Bryson, Peter, Dharsee, Moyez, Evans, Kenneth, Feilotter, Harriet E, Park, Paul C, Squire, Jeremy A
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840597/
https://ncbi.nlm.nih.gov/pubmed/24237932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-13-549
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