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Generation and Characterization of a Conditional Deletion Allele for Lmna in Mice
Extensive efforts have been devoted to study A-type lamins because mutations in their gene, LMNA in humans, are associated with a number of diseases. The mouse germline mutations in the A-type lamins (encoded by Lmna) exhibit postnatal lethality at either 4 - 8 postnatal (P) weeks or P16 - 18 days,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840542/ https://ncbi.nlm.nih.gov/pubmed/23998933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.08.082 |
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