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Generation and Characterization of a Conditional Deletion Allele for Lmna in Mice

Extensive efforts have been devoted to study A-type lamins because mutations in their gene, LMNA in humans, are associated with a number of diseases. The mouse germline mutations in the A-type lamins (encoded by Lmna) exhibit postnatal lethality at either 4 - 8 postnatal (P) weeks or P16 - 18 days,...

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Hlavní autoři: Kim, Youngjo, Zheng, Yixian
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840542/
https://ncbi.nlm.nih.gov/pubmed/23998933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.08.082
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