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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
The p38 MAPK pathway is an important regulator of many cellular responses. It is well established that p38 MAPK signalling negatively regulates epithelial cell transformation, but enhanced p38 MAPK activity has been also correlated with bad clinical prognosis in some tumour types. Here, we provide g...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Blackwell Publishing Ltd
2013
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オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840490/ https://ncbi.nlm.nih.gov/pubmed/24115572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302732 |
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