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Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK

The p38 MAPK pathway is an important regulator of many cellular responses. It is well established that p38 MAPK signalling negatively regulates epithelial cell transformation, but enhanced p38 MAPK activity has been also correlated with bad clinical prognosis in some tumour types. Here, we provide g...

詳細記述

保存先:
書誌詳細
主要な著者: Pereira, Lorena, Igea, Ana, Canovas, Begoña, Dolado, Ignacio, Nebreda, Angel R
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840490/
https://ncbi.nlm.nih.gov/pubmed/24115572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201302732
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