Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through MER Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

RATIONALE: Efficient clearance of apoptotic cells (efferocytosis) is a prerequisite for inflammation resolution and tissue repair. Following myocardial infarction (MI), phagocytes are recruited to the heart and promote clearance of dying cardiomyocytes (CMs). The molecular mechanisms of efferocytosi...

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Hauptverfasser: Wan, Elaine, Yeap, Xin Yi, Dehn, Shirley, Terry, Rachael, Novak, Margaret, Zhang, Shuang, Iwata, Shinichi, Han, Xiaoqiang, Homma, Shunichi, Drosatos, Konstantinos, Lomasney, Jon, Engman, David M., Miller, Stephen D., Vaughan, Douglas E., Morrow, John P., Kishore, Raj, Thorp, Edward B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840464/
https://ncbi.nlm.nih.gov/pubmed/23836795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301198
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