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Hypoxia Induced Tumor Metabolic Switch Contributes to Pancreatic Cancer Aggressiveness

Pancreatic ductal adenocarcinoma remains one of the most lethal of all solid tumors with an overall five-year survival rate of only 3–5%. Its aggressive biology and resistance to conventional and targeted therapeutic agents lead to a typical clinical presentation of incurable disease once diagnosed....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Vasseur, Sophie, Tomasini, Richard, Tournaire, Roselyne, Iovanna, Juan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840441/
https://ncbi.nlm.nih.gov/pubmed/24281221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers2042138
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