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Detection of an altered DNA conformation at specific sites in chromatin and supercoiled DNA.

We show that bromoacetaldehyde, which reacts selectively at the N-1 and N-6 positions of unpaired adenine and at the N-3 and N-4 positions of unpaired cytosine residues reacts with chromosomal DNA in intact cells at probable regulatory sequences near active genes. A region of about 200 base pairs 5&...

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Bibliografski detalji
Glavni autori: Kohwi-Shigematsu, T, Gelinas, R, Weintraub, H
Format: Artigo
Jezik:Inglês
Izdano: 1983
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC384043/
https://ncbi.nlm.nih.gov/pubmed/6308620
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