Inhibition of autophagy enhances apoptosis induced by proteasome inhibitor bortezomib in human glioblastoma U87 and U251 cells

Glioblastoma is the most aggressive cerebral gliomas. Despite advances in therapies, the prognosis is still very poor. Therefore, novel therapeutic strategies are required. As a proteasome inhibitor, bortezomib has shown its efficacy as an active antitumor agent against a variety of tumors. However,...

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Bibliographic Details
Main Authors: Zhang, Xudong, Li, Weiming, Wang, Chunlan, Leng, Xiangyang, Lian, Shulin, Feng, Jingbin, Li, Jinliang, Wang, Hailiang
Format: Artigo
Language:Inglês
Published: Springer US 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840293/
https://ncbi.nlm.nih.gov/pubmed/24104452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-013-1835-z
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