Cyclooxygenase-1 inhibition attenuates angiotensin II-salt hypertension and neurogenic pressor activity in the rat

Cyclooxygenase (COX)-derived prostanoids contribute to angiotensin II (ANG II) hypertension (HTN). However, the specific mechanisms by which prostanoids act are unclear. ANG II-induced HTN is caused partly by increased sympathetic nervous system activity, especially in a setting of high dietary salt...

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Main Authors: Asirvatham-Jeyaraj, Ninitha, King, Andrew J., Northcott, Carrie A., Madan, Shivanshu, Fink, Gregory D.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840267/
https://ncbi.nlm.nih.gov/pubmed/24014677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00245.2013
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