Targeted afferent renal denervation reduces arterial pressure but not renal inflammation in established DOCA-salt hypertension in the rat

Recent preclinical studies show renal denervation (RDNx) may be an effective treatment for hypertension; however, the mechanism remains unknown. We have recently reported total RDNx (TRDNx) and afferent-selective RDNx (ARDNx) similarly attenuated the development of deoxycorticosterone acetate (DOCA)...

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Udgivet i:Am J Physiol Regul Integr Comp Physiol
Main Authors: Banek, Christopher T., Gauthier, Madeline M., Baumann, Daniel C., Van Helden, Dusty, Asirvatham-Jeyaraj, Ninitha, Panoskaltsis-Mortari, Angela, Fink, Gregory D., Osborn, John W.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032306/
https://ncbi.nlm.nih.gov/pubmed/29513561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00416.2017
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