Transcriptional and phenotypic changes in aorta and aortic valve with aging and MnSOD deficiency in mice

The purpose of this study was to characterize changes in antioxidant and age-related gene expression in aorta and aortic valve with aging, and test the hypothesis that increased mitochondrial oxidative stress accelerates age-related endothelial and aortic valve dysfunction. Wild-type (MnSOD(+/+)) an...

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Detaylı Bibliyografya
Asıl Yazarlar: Roos, Carolyn M., Hagler, Michael, Zhang, Bin, Oehler, Elise A., Arghami, Arman, Miller, Jordan D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2013
Konular:
Call for Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840262/
https://ncbi.nlm.nih.gov/pubmed/23997094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00735.2012
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