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Effects of Altering Mitochondrial Antioxidant Capacity on Molecular and Phenotypic Drivers of Fibrocalcific Aortic Valve Stenosis

Background: While a small number of studies suggest that oxidative stress has an influential role in fibrocalcific aortic valve disease (FCAVD), the roles of specific antioxidant enzymes in progression of this disease remain poorly understood. Here, we focused on selectively altering mitochondrial-d...

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Publicat a:Front Cardiovasc Med
Autors principals: Roos, Carolyn M., Zhang, Bin, Hagler, Michael A., Verzosa, Grace C., Huang, Runqing, Oehler, Elise A., Arghami, Arman, Miller, Jordan D.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8263922/
https://ncbi.nlm.nih.gov/pubmed/34250048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2021.694881
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