Increased vascular smooth muscle cell stiffness: a novel mechanism for aortic stiffness in hypertension

Increased vascular stiffness is fundamental to hypertension, and its complications, including atherosclerosis, suggest that therapy should also be directed at vascular stiffness, rather than just the regulation of peripheral vascular resistance. It is currently held that the underlying mechanisms of...

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Main Authors: Sehgel, Nancy L., Zhu, Yi, Sun, Zhe, Trzeciakowski, Jerome P., Hong, Zhongkui, Hunter, William C., Vatner, Dorothy E., Meininger, Gerald A., Vatner, Stephen F.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840243/
https://ncbi.nlm.nih.gov/pubmed/23709594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00232.2013
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