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Role of NADPH oxidase NOX5-S, NF-κB, and DNMT1 in acid-induced p16 hypermethylation in Barrett's cells

Inactivation of tumor suppressor genes via promoter hypermethylation may play an important role in the progression from Barrett's esophagus (BE) to esophageal adenocarcinoma (EA). We have previously shown that acid-induced p16 gene promoter hypermethylation may depend on activation of NADPH oxi...

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Bibliografski detalji
Glavni autori: Hong, Jie, Li, Dan, Wands, Jack, Souza, Rhonda, Cao, Weibiao
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840198/
https://ncbi.nlm.nih.gov/pubmed/24025864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00080.2013
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