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Testing an alternative model for the ribosomal peptide elongation cycle.

A kinetic analysis of poly(U)-dependent poly(Phe) synthesis with [14C]tRNAPhe and [3H]phenylalanine demonstrated that, in the course of efficient poly(Phe) synthesis, two tRNAs are present per 70S ribosome at all times, although at least 70% of the poly(Phe)-tRNAPhe is found at the peptidyl-tRNA (P)...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rheinberger, H J, Nierhaus, K H
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC384007/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6348767/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.14.4213
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