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The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction

In recent years, α-tomatine has been studied for its anticancer activity. In the present study, we focused on the cytotoxic effect of α-tomatine in the MCF-7 human breast adenocarcinoma cell line, its mechanism of action, biotransformation and stability in the culture medium. We observed an inhibiti...

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Detalhes bibliográficos
Main Authors: SUCHA, LENKA, HROCH, MILOS, REZACOVA, MARTINA, RUDOLF, EMIL, HAVELEK, RADIM, SISPERA, LUDEK, CMIELOVA, JANA, KOHLEROVA, RENATA, BEZROUK, ALES, TOMSIK, PAVEL
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839989/
https://ncbi.nlm.nih.gov/pubmed/24100733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2013.2778
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