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Biogenesis of poxviruses: role for the DNA-dependent RNA polymerase II of the host during expression of late functions.

The participation of host RNA polymerase II in the vaccinia life cycle was examined by comparing efficiency of multiplication after treating the Ama+ sensitive and Ama 102 drug resistant lines with alpha-amanitin. In the latter, resistance is due to a mutation in RNA polymerase II. The toxin profoun...

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Main Authors: Silver, M, McFadden, G, Wilton, S, Dales, S
格式: Artigo
語言:Inglês
出版: 1979
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC383990/
https://ncbi.nlm.nih.gov/pubmed/226996
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