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Biogenesis of poxviruses: role for the DNA-dependent RNA polymerase II of the host during expression of late functions.

The participation of host RNA polymerase II in the vaccinia life cycle was examined by comparing efficiency of multiplication after treating the Ama+ sensitive and Ama 102 drug resistant lines with alpha-amanitin. In the latter, resistance is due to a mutation in RNA polymerase II. The toxin profoun...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Silver, M, McFadden, G, Wilton, S, Dales, S
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1979
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383990/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226996/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.8.4122
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