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Lulu Regulates Shroom-Induced Apical Constriction during Neural Tube Closure

Apical constriction is an essential cell behavior during neural tube closure, but its underlying mechanisms are not fully understood. Lulu, or EPB4.1l5, is a FERM domain protein that has been implicated in apical constriction and actomyosin contractility in mouse embryos and cultured cells. Interfer...

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Autors principals: Chu, Chih-Wen, Gerstenzang, Emma, Ossipova, Olga, Sokol, Sergei Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839891/
https://ncbi.nlm.nih.gov/pubmed/24282618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081854
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