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GEF-H1 functions in apical constriction and cell intercalations and is essential for vertebrate neural tube closure
Rho family GTPases regulate many morphogenetic processes during vertebrate development including neural tube closure. Here we report a function for GEF-H1/Lfc/ArhGEF2, a RhoA-specific guanine nucleotide exchange factor that functions in neurulation in Xenopus embryos. Morpholino-mediated depletion o...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Company of Biologists
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4038946/ https://ncbi.nlm.nih.gov/pubmed/24681784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.146811 |
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