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Harnessing immune responses in the tumor microenvironment: All signals needed

An agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine is well tolerated in patients with advanced pancreatic adenocarcinoma. The combination results in induction of cytokines, B cell activation, and clinical responses. These findings support testing immunotherapies in comb...

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Bibliografiska uppgifter
Huvudupphovsmän: Le, Dung T., Jaffee, Elizabeth M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839670/
https://ncbi.nlm.nih.gov/pubmed/24097857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2424
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