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Harnessing immune responses in the tumor microenvironment: All signals needed
An agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine is well tolerated in patients with advanced pancreatic adenocarcinoma. The combination results in induction of cytokines, B cell activation, and clinical responses. These findings support testing immunotherapies in comb...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839670/ https://ncbi.nlm.nih.gov/pubmed/24097857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-2424 |
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