Environmental factors determine DAP12 deficiency to either enhance or suppress immunopathogenic processes

DNAX-activation protein 12 (DAP12), a transmembrane adapter, plays a major role in transducing activation signals in natural killer cells and various myeloid cells. Quantitative RT-PCR detected in normal mouse eyes considerable levels of DAP12 and multiple DAP12-coupled receptors, in particular TREM...

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Detalhes bibliográficos
Main Authors: Montalvo, Vanessa, Quigley, Laura, Vistica, Barbara P, Boelte, Kimberly C, Nugent, Lindsey F, Takai, Toshiyuki, McVicar, Daniel W, Gery, Igal
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839651/
https://ncbi.nlm.nih.gov/pubmed/23906311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12158
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