Analog of Somatostatin Vapreotide Exhibits Biological Effects In Vitro via Interaction with Neurokinin-1 Receptor

OBJECTIVES: Vapreotide, a synthetic analog of somatostatin, has analgesic activity most likely mediated through the blockade of neurokinin-1 receptor (NK1R), the Substance P (SP) preferring receptor. The ability of vapreotide to interfere with other biological effects of SP has yet to be investigate...

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Hauptverfasser: Spitsin, Sergei, Tuluc, Florin, Meshki, John, Lai, Jian Ping, Tustin, Richard, Douglas, Steven D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839635/
https://ncbi.nlm.nih.gov/pubmed/23921645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350468
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