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Translesion DNA Synthesis and Mutagenesis in Prokaryotes
The presence of unrepaired lesions in DNA represents a challenge for replication. Most, but not all, DNA lesions block the replicative DNA polymerases. The conceptually simplest procedure to bypass lesions during DNA replication is translesion synthesis (TLS), whereby the replicative polymerase is t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839610/ https://ncbi.nlm.nih.gov/pubmed/24296168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012682 |
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