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Molecular analysis of chromosome-mediated gene transfer.

Metaphase chromosomes isolated from a cell line carrying the thymidine kinase (TK) gene of herpes simplex virus type I were used to transform the TK-deficient cell line LMTK- to the TK+ phenotype. Four independent transformants were isolated, all of which expressed virus-specific TK. Each of the fou...

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Autores principales: Scangos, G A, Huttner, K M, Silverstein, S, Ruddle, F H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1979
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC383961/
https://ncbi.nlm.nih.gov/pubmed/226993
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