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Helicase Activation and Establishment of Replication Forks at Chromosomal Origins of Replication
Many replication proteins assemble on the pre-RC-formed replication origins and constitute the pre-initiation complex (pre-IC). This complex formation facilitates the conversion of Mcm2–7 in the pre-RC to an active DNA helicase, the Cdc45–Mcm–GINS (CMG) complex. Two protein kinases, cyclin-dependent...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839609/ https://ncbi.nlm.nih.gov/pubmed/23881938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a010371 |
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