Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription

Rev-Erbα and Rev-Erbβ are nuclear receptors that regulate the expression of genes involved in the control of circadian rhythm(1,2), metabolism(3,4), and inflammatory responses(5). Rev-Erbs function as transcriptional repressors by recruiting NCoR/HDAC3 co-repressor complexes to Rev-Erb response elem...

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Detalhes bibliográficos
Principais autores: Lam, Michael T.Y., Cho, Han, Lesch, Hanna P., Gosselin, David, Heinz, Sven, Tanaka-Oishi, Yumiko, Benner, Christopher, Kaikkonen, Minna U., Kim, Aneeza S., Kosaka, Mika, Lee, Cindy Y., Watt, Andy, Grossman, Tamar R., Rosenfeld, Michael G., Evans, Ronald M., Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3839578/
https://ncbi.nlm.nih.gov/pubmed/23728303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12209
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